Nilson E. Souza Filho, Vinícius V. G. Mariucci, Gustavo S. Dias, Wesley Szpak, Patrícia H. P. Miguez, Ed H. Madureira, Antonio Medina Neto, Mauro L. Baesso e Antonio C. Bento

APPLIED PHYSICS LETTERS – Volume: 103; Issue: 14; Article Number: 144104; DOI: 10.1063/1.4823986

Intravaginal devices composed of polyhydroxybutyrate/polycaprolactone blends incorporating progesterone were used over eight days in crossbred cow ovariectomized, and then analyzed with photoacoustic methods, measuring the absorption spectra, thermal diffusivity, and inspecting its degradation by means of scanning electron microscopy. The characteristic time found for progesterone release was TR 53 h, and the typical time found for biodegradation was TB 30 h. Morphological analysis complements the study showing that release of progesterone and biodegradation of the blend occurs on sample surface.